Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHLNSSIDKKMTTLNILFKTTSLCLAMALLVGCNDNDDNDSSTPAPRSNQTVNILAFNDFHGNLEPPKRYVEAANPNDASQTVRIPVGGVSYFADAIKKLKAQNPNNVVVSAGDLISASPLTSSLFLDEPTIEVMNDIQIDFNAVGNHEFDRGTDELRRL-QNGGCQQYTSTAPCQINKNFSGAKFNFLAANVAMKNDTS---KTIFPAYKVKTYGGIPVAFIGLTLKATPSIVSAAGIKDVEFRDEADTVNALIPELQKQGIEAIVVVVHEGAAPSTKLNQKTCDGLSGPILGILDRLNPAVDIVVSGHTHQSYICDY--------------ATKNPAKPFLLTSAGQYGTLITDIKVGLDGKTGDIIKKDAKQIPVQSEAYTSGTTTVSLTDLYQKFSKTPSIEAILDKYRQAVTTISGRVVGTSTAVVS--RTQVESGESPLGDMIADAQQAAALQA----SNQGSDFTLMNPGGVRADLLINSSNQITFGDIFAVQPFGNSIVTLSLTGKQIRDVLEQQWSGANANSPRILQPSKELSYQYAANTSVSPRASNIMV--------AGSPLVDTKVYRVTVNSFLADGGDNFTVLKEGQNR-VGGGQDIDALESYVAQNSKDSPLIIPATTRIKVIK 4H2G Chain:A ((23-545)) ------------------------------------------------PWELTILHTNDVHSRLEQTSEDSSKC------VDASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFT-VYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKE-------------------AKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPG--TNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDK---------------LIAQKV-RGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERG-NVISSHGNPILLD-----------------SSIPEDPSIKADINKWRIKLDDYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHADEMFWNHVSMCILNGGGIRSPIDERNDGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVG-GIHVVYDLSRKPGDRVVKLDVLCTACAVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISKMK---VIYPAVEGRIKF--

General information: TITO was launched using: RESULT: Template: 4H2G.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2903 29446 10.14 60.09 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : 10.14 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.413

(partial model without unconserved sides chains): PDB file : Tito_4H2G.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4H2G-query.scw PDB file : Tito_Scwrl_4H2G.pdb: