Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------MKIRILTIGQKMPAWVLTGFED-YF-KRIQPFV--------------------QTQVIKLPMAKRGKNDSEADILKYCQIEGESILNALKPNETLIALEVGGRE---LSTEKLADTMKQWMLEGNDVALAIGG-PDGLSDQVRKAAAW------HWSLSKLTMPHPLVRILLIEQLYRAMS-INHNHPYHRA------------- 3IC6 Chain:A ((4-220)) LKPALPDYLGNIRIILTRTSHPANIGSAARAMKTMGLHRLTIVTPNLMATPMTENPPVFNPDDVQSFALPEESFILASGAADVLHNAEIV-ATLDEALADTTIACALTSRRRTAPLQTPRDLVPELLQAANRGEKVALVFGNETFGLSIEEVRACNRLMTINGNPDYFSLNLAQAVQVVCYEIFSQTDSPMTHLQQHAATHEQIKGMLAHMESV

General information: TITO was launched using: RESULT: Template: 3IC6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 745 3111 4.18 19.69 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : 4.18 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.424

(partial model without unconserved sides chains): PDB file : Tito_3IC6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IC6-query.scw PDB file : Tito_Scwrl_3IC6.pdb: