Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVVAFKQVDVFTSQAFKGNPVAVIMDASTLTSEQMQAIANWTNLSETTFVLPAIDSQADYQVRIFTPQSELPFAGHPTIGTAYALLEAGLVKAKEGQLVQQCAAGLVTLTVNDSNHISFEL-PK---PKIT-PLDALQTQKLAEILKCK--INT-QWNAALVDVGARWVVLQAVNAKAVLASQPDLNALKQFSLEMKVTGSTIYGFYEESNEQKRIEVRSFAPAYGVNEDPVCGSGNGSVASFIRYHSILPA--QNDVMLSSQGQALGREGQLQLELHQ-----DKILVGGAAVTCIDGTIKL 1SDJ Chain:A ((11-306)) HMKPQVYHVDAFTSQPFRGNSAGVVFPADNLSEAQMQLIARELGHSETAFLLHSD--DSDVRIRYFTPTVEVPICGHATVAAHYVRAKVLGLG--NCTIWQTSLAGKHRVTIEKHN-DDYRISLEQGTPGFEPPLEGETRAAIINALHLTEDDILPGLPIQVATTGHSKVMIPLKPEVDIDALSPDLNALTAISKKIGCNGFFPFQIRPG--K-NETDGRMFSPAIGIVEDPVTGNANGPMGAWLVHHNVLPHDGNVLRVKGHQGRALGRDGMIEVTVTIRDNQPEKVTISGTAVILFHAEWAI

General information: TITO was launched using: RESULT: Template: 1SDJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1635 -39485 -24.15 -140.52 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -24.15 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.489

(partial model without unconserved sides chains): PDB file : Tito_1SDJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1SDJ-query.scw PDB file : Tito_Scwrl_1SDJ.pdb: