Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEFRGGRKMEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKRRVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQLMIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFEKLE-AFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG 1JYH Chain:A ((1-154)) -----------------------MNYEIKQEEKRTVAGFHLVGPWEQ-TVKKGFEQLMMWVDSKNIVP-K-------------EWVAVYY-DNPD----ETPAEKLRCDTVVTVPGYFTL--------------PENSEGVILTEITGGQYAVAVARVVGDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGA--EDGYWDIEMYVAVQP-

General information: TITO was launched using: RESULT: Template: 1JYH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 651 -39046 -59.98 -255.20 target 2D structure prediction score : 0.38 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -59.98 2D Compatibility (Sec. Struct. Predict.) : 0.38 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.306

(partial model without unconserved sides chains): PDB file : Tito_1JYH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JYH-query.scw PDB file : Tito_Scwrl_1JYH.pdb: