Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPLGLLWLGLALLGALHAQAQDSTSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLA--GNAILREDKDPQK-MYATIYELKEDKSYNVTSVLFRKK-KCDYWIRTFVPGCQPG----EFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKKV-SQNREYFKITLYGRT-KELTSELKENFIRFSKSLG--LPENHIVFPVPIDQCIDG 1QQS Chain:A ((1-174)) ---------------------TSDLI--PAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAI--LREDKDPQKMYATIYEEKE-DASYNVTSVLFRK-KKCDYAIRTFVPGCQ--PGEFTLGN--IKSYPGLTSYLVRVVSTNYNQHAMVFFKKVSQNR-EYFKITLYGRTK-ELTSELKNNFIRFSKSLGLPENH--IVFPVPIDQCID-

General information: TITO was launched using: RESULT: Template: 1QQS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 697 3663 5.26 22.61 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : 5.26 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.638

(partial model without unconserved sides chains): PDB file : Tito_1QQS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QQS-query.scw PDB file : Tito_Scwrl_1QQS.pdb: