Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence LIIGFISKQYVTSLLLNEPDGTFLLRFSDSE-IGGITIAHVIRGQDGSPQIENIQPFSAKDLSIRSLGNRIRDLA----------QLKNLY 1YVL Chain:A ((577-668)) CIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQ--EPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLY

General information: TITO was launched using: RESULT: Template: 1YVL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 252 -17976 -71.33 -230.46 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -71.33 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.610

(partial model without unconserved sides chains): PDB file : Tito_1YVL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YVL-query.scw PDB file : Tito_Scwrl_1YVL.pdb: