Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVSTSTVIRKLREFKFETDWTKLPKVMSWDEYSFKKSKMSFIAQDF---ESKSILAILD---GRTHAVIRNHFQRYQREVRELVEVITMDMYSPYYRLAKQLFPKAKIVLDRFHIVQHLSRAMN-----RVRIQIMNQFDRKSLEYRALKRFWNPRFFV--SRLGLNQSTGLIYYARIASSSVRNDSISPRFECT---------- 5M1P Chain:A ((3-189)) AMNSVFSGLDMLILLPYERRGTRL--VVE----DYRPDHIYCIGADFGKNQDYSVFSVLDLDTGAIACLERMNGATWSDQVARLKALSED-------------YGHAYVVADTWGVGDAIAEELDAQGINYTPLPVKSSSVKEQLISNLALLMEKGQVAVPNDKTILDELRNFRYYRTASGNQVMRAYGRGHDDIVMSLALAYSQY

General information: TITO was launched using: RESULT: Template: 5M1P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 716 -23727 -33.14 -144.68 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -33.14 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.223

(partial model without unconserved sides chains): PDB file : Tito_5M1P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5M1P-query.scw PDB file : Tito_Scwrl_5M1P.pdb: