Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIFATSQVNPLTNSSVRNLRPKQRRLF-------MFWNLVHYE--FKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQESQATMLLFLATVFGGLMLTLAISTIFLIIK------RFKGSVYDRQGYLT--------LTLPVSEHHIITAKLIGAFI----WSLISTAVL-----ALSAVIILAL---------------TAPEWIPLSYVITFVETHLPQIFLTGISFLLNTISGILCIYLAISIGQLFNE-----YRTALAVAVYIGIQIVIGFIELFF-----------NLSSNFYVNSLVGLNDHFYMGAGIAIVEELIFIAIFYLGTYYILRNK-VNLL 1D0V Chain:A ((4-349)) LHALLRDIPAPDAEAMARTQQHIDGLLKPPGSLGRLETLAVQLAGMPGLNGTPQVGEKAVLVMCADHGVWDEGVAVSPKIVTAIQAANMTRGTTGVCVLAAQAGAKVHVIDVGIDAEPIPGVVNMRVARGCGNIAVGPAMSRLQAEALLLEVSRYACDLAQRGVTLFGVGELGMANTTPAAAMVSVFTGSDAKEVVGIGANLPPSRIDNKVDVVRRAIAINQPNPRDGIDVLSKVGGFDLVGMTGVMLGAARCGLPVLLDGFLSYSAALAACQIAPAVRPYLIPSHFSAEKGARIALAHLSMEPYLHMAMRLGEGSGAALAMPIVEAACAMFHNMGELAASNIVLP

General information: TITO was launched using: RESULT: Template: 1D0V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1620 -155378 -95.91 -550.98 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -95.91 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.317

(partial model without unconserved sides chains): PDB file : Tito_1D0V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1D0V-query.scw PDB file : Tito_Scwrl_1D0V.pdb: