Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGKPEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY 3OEI Chain:P ((13-96)) RSVNFDPDAWEDFLFWLAADRKTARRITRLIGEIQRDPFSGIGKPEPLQGELSGYWSRRIDDEHRLVYRAGDDEVTMLKARYHY

General information: TITO was launched using: RESULT: Template: 3OEI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain P - contact count / total energy / energy per contact / energy per residue : 338 -36149 -106.95 -430.35 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain P : 0.83 3D Compatibility (PKB) : -106.95 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.693

(partial model without unconserved sides chains): PDB file : Tito_3OEI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OEI-query.scw PDB file : Tito_Scwrl_3OEI.pdb: