Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------MFVNRLM------AILNP-IMMGISS-GLSVAIYWIGAYVINDAAPIARLPFFSDMIVFMSYAM-------------------------------------------------------------- 3CWX Chain:A ((47-176)) EVNPDIIKDEVFDFVIVNRVLKKIKDLKHYDPMIEK-IFEMGLNVEIQ------IN--------PEVKDFFTFKSISTTNKQRCFLSLRGETREILCDNKLYNMLLAVFNSYDPNDLLKHISTVESLKKIFYTITCEAVY

General information: TITO was launched using: RESULT: Template: 3CWX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 77 -7343 -95.36 -179.10 target 2D structure prediction score : 0.24 Monomeric hydrophicity matching model chain A : 0.56 3D Compatibility (PKB) : -95.36 2D Compatibility (Sec. Struct. Predict.) : 0.24 1D Compatibility (Hydrophobicity) : 0.56 QMean score : 0.072

(partial model without unconserved sides chains): PDB file : Tito_3CWX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CWX-query.scw PDB file : Tito_Scwrl_3CWX.pdb: