Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVVAQQLGQWAEQTALKLLKEQNYEWVASNYHSRRGEVDLIVKRGNELIFVEVKARGQGNYGQACEMVTLSKQKKIIKTAMRFLQRYPSYQDFYCRFDVICFDFPQKIAK-TVQQDFSKFHYDLQWIENAFTLD------ 1HH1 Chain:A ((9-140)) --------SAVERNIVSRLRDKGFAVVRAP----APIPDIIALKNGVIILIEMKSRKDIEGK---IYVRREQAEGIIEFARKSGGSLFLGVKKPGVLKFIPFEKLRRTETGNYVADSEIEGLDLEDLVRLVEAKISRTLD

General information: TITO was launched using: RESULT: Template: 1HH1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 527 -36679 -69.60 -310.84 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -69.60 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.442

(partial model without unconserved sides chains): PDB file : Tito_1HH1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1HH1-query.scw PDB file : Tito_Scwrl_1HH1.pdb: