Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----------------------------------------------------------MIEELLPFYEKQLQEFGQQSREFAQKYPKIAQRLSLNQEQIDDP----HIERLIQAFSLIAARIDKKLTDSYDVFTRSLFEVMFPQYLRHFPACSVVS-----------FEDINKIKQLTE--PHLVPHHTVLKSRSF--KGVQCEFNTTQDVRLLPIHL------------------------SGLDFKTTPSAHM--HLNQNATLSLKFEIFNNAHAC------LTDEKLPIYLDAISNFP---LQVLDSIFKK-----GTSFA-----------VKYGQIIVELSKNPFELTGFAEQESLLPLDQHTHHAYRLLMEYFCFPEK-----------FSYLKLDLDFLKRIPQHVSEFELLIHFKLNLN-DQAVVRNY--SELNIANFKLFTTPVINLFEKYAEPQKIVHKQLEYPLV-TDAHHPEFYQVYS---ILEMNMVREKTNQEESYVPVLPFFAMSHYHNDTARFFYSVNYQKLQSNFVEMGYSI----ISKNLNPFSTRSD--------FISTKLLCSNRDLPHEAL-----GQSNNVLNLNDSSLARR--------------------AIVLKRPTKPYKFEQGQSEQWRVISHLSLNSLALMKGDAVSLVKELLALYNLPQSKENYLIIESIKKLEF-----------SLTHKLVDGKPFPMFVRGVKAELQIDSSV-FR--GHSLYIFSQLLS------RVFNLKVQIN-------SFVDLVVKDYSSQQELYQ----CSQNVGGKTLL----------------------------------------------------------------------- 5DZT Chain:A ((4-992)) NLINVLSINERCFLLKQSGNEKYDIKNLQAWKERKSVLKQDDLDYLIKYKYESLDNFGLGITPIENFPDKEVAIQYIKDQSWYIFFESILDSYNDSEEQLLEVDASYPFRYFLQYARLFLLDLNSELNICTKEFIINLLEILTQELIHLTSKTLVLDLHRFIYYLKKRFNSKKDIIAFYTCYPELM-RITVVRMRYFLDNTKQMLIRVTEDLPSIQNCFNIQSSELNSISESQGDSHSRGKTVSTLTFSDGKKIVYKPKINSENKLRDFFEFLNKELEADIYIVKKVTRNTYFYEEYIDNIEINNIEEVKKYYERYGKLIGIAFLFNVTDLHYENIIAHGEYPVIIDNETFFQQNIPIEFGNSATVDAKYKYLDSIMVTGLVPKNTPIMNNEKISFISYEKYIVTGMKSILMKAKDSKKKILAYINNNLQNLIVRNVIRPTQRYADMLEFSYH-PNCFSNAIEREKVLHNMWAYPYKNKKVVHYEFSDLIDGDIPIFYNNISKTSLIASDGCLVEDFYQES-ALNRCLNKINDLCDEDISIQTVWLEIALNIYNPYKYINDLKNQNSNKYIYTGLELNGKIIQACQKIEKKIFKRAIFNKKTNTVNWIDIKLDQDWNVGILNNNMYDGLPGIFIFYVALKYITKNHKYDYVIECIKNSIYTIPSEDILSAFFGKGSLIYPLLVDYRLNNDINSLNVAVEIADMDWIHGHNSIIKVLLLLSEITEDEKYRKFSLEIFEKLSEEPYFNFRGFGHGIYSYVHLLSKFNRIDKANSLLHKIKNNSWCKGTVGELLATDINKTIEYKNKDCLCHGNAGTLEGLIQLAKKDPETYQYKKNKLISYMLKYFEKNNTLKVAGSEYLESLGFFVGISGVGYELLRNLDSEIPNALLFE

General information: TITO was launched using: RESULT: Template: 5DZT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2672 58563 21.92 97.60 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 21.92 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.169

(partial model without unconserved sides chains): PDB file : Tito_5DZT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DZT-query.scw PDB file : Tito_Scwrl_5DZT.pdb: