Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKDIYVEFRGKYKVDGESRDSEHKGWLEVNSWSHNIRQPKSATSSSVGGHTAERVEHSDMVFVKDLDATSPKLWEACSAGYTFDEVQIDFYRANGDKRIKYLQIKLKHVLVSSVTPTVNEE-GVPTEAFGLKYAAVEWTYNQQDINGTAKG-AVTKKWSLSNNTASYAA 1Y12 Chain:C ((2-161)) AVDMFIKIG-D--VKGESKDKTHAEEIDVLAWSWGMSQSGSMHMG--GGGGAGKVNVQDLSFTKYIDKSTPNLMMACSSGKHYPQAKLTIRKAGGENQVEYLIITLKEVLVSSVSTGGSGGEDRLTENVTLNFAQVQVDYQPQKADGAKDGGPVKYGWNIRQNVQ----

General information: TITO was launched using: RESULT: Template: 1Y12.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 686 -11105 -16.19 -70.28 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain C : 0.77 3D Compatibility (PKB) : -16.19 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.555

(partial model without unconserved sides chains): PDB file : Tito_1Y12.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Y12-query.scw PDB file : Tito_Scwrl_1Y12.pdb: