Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNVRHSFPKNIFRAYDIRGKLS-YLTTDVVRSIAYGLAQQYKQAEQTQLIIGYDARLTSPAYAHLIEEILVEQGLNVTNIGCCSTPMMYYIAR--------EFG-GNGIMVTASHNPKSDNGIKWILRGEPPSPEMIQQVGEFAQTYVPTHTISLLELSTPQFNSKFCKKYQQAIFNDIQLKRPLKVVLDGLHGSAGHCSKLVLEKMGCEVIALRTTPNGEFPDHAPDPSHAAHLKELRKTIIEQGADIGIALDGDGDRVVLLDEKANILTADRLLSLFAQMCLEQQPDKEIVFDVKCSLMVQRTVERLGGKPKMIRTGSSFLRAYLSQSNGNAIFGGEYAGHYVFNDGRGFGYDDGLYAALRVMEYFTKSSATTISDLFSNYPERCCTEDTYIGTHQSDPK-HVLQDIEILSHRLG-ARISKIDGVRLDFDDGFGIIRASNTGEYFTVRFDADNPLRLKEIQQKFIDMLQERYPQIAQELSEA 3UW2 Chain:A ((22-482)) -----MISQSIFKAYDIRGVIGKTLDADVARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELVGALADGLRAAGVDVVDVGMVPTPVGYFAASVPLALSGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGDQIQGLYKRIVD-ARFE----TGSGSYE-QYDVADQYVERIVGDIKLTRPLKLVVDAGNGVAGPLATRLFKALGCELVELFTDIDGNFPNHHPDPAHPENLQDVIAKLKATDAEIGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRNLARWVREKGGEPLMWKTGHSLVKAKLRE-T-GAPLAGEMSGHVFFKD-RWYGFDDGLYTGARLLEILARV-A-DPSALLNGLPNAVSTPELQL-------NVKLIDKLRADAKFDGADEVVTIDGLRVEYPDGFGLARSSNTTPVVVLRFEATSDAALARIQDDFRRALKAAKPGAN------

General information: TITO was launched using: RESULT: Template: 3UW2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2746 41533 15.12 93.75 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : 15.12 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.593

(partial model without unconserved sides chains): PDB file : Tito_3UW2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UW2-query.scw PDB file : Tito_Scwrl_3UW2.pdb: