Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNQLDQRPIIALDFSTRQEVEDFL-RFFPKEEKLFVKIGMELFYQEGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAAMRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLDGVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGRPITQSTNPYKAYQTIQTEWS 3UWQ Chain:B ((27-252)) ----DPKVIVALDYDNLADALAFVDKIDPSTCRL--KVGKEMFTLFGPDFVRELHKRGFSVFLDLKFHDIPNTCSKAVKAAAELGVWMVNVHASGGERMMAASREILE---PYGKERPLLIGVTVLTSMESADLQGIGILSAP-QDHVLRLATLTKNAGLDGVVCSAQEASLLKQHLGREFKLVTPGIRPAGS----QRRIMTPAQAIASGSDYLVIGRPITQAAHPEVVLEEINS---

General information: TITO was launched using: RESULT: Template: 3UWQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1145 -31876 -27.84 -144.23 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain B : 0.79 3D Compatibility (PKB) : -27.84 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.616

(partial model without unconserved sides chains): PDB file : Tito_3UWQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UWQ-query.scw PDB file : Tito_Scwrl_3UWQ.pdb: