Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREMPFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRG-LEVYPEGFLEYLQNFEFKATVRSAREGELVFANEPL--IQVEGPLAHCQLVETALLNMVNFQ---------------TLIATKAARIKSVI-----GEDPLLEFGTRRAQELDAA---VWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYG-------NDYEAFMAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVREQLDAAGFT-EAKI-YASNDLDEATILNLKM--QKAKIDVWGVGTKLITAYD---------QPALGAVFKLVSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEEAIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEEYKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA 4HL7 Chain:A ((11-408)) -----HIIRSLLDLDAYKINMMQAIHHFYP-DVSVRYELIVRSEEDAS--GLLDAIRQEIAHLGTLRFSDADIHYLTQHAPHLKATFLQSLRYFHFV-PQEQVEMGIVK----QQLRISIRGSWRDTILYETLVMAIVSEVRSRQRWAEVPADLPLKVLKTKLDQLKAEIERRGINNFSLTEMGTRRRFSSQVQRDVLACLKQEIPQWVLGTSNYHFAREFDLKPIGTIAHEWFMGHQALVNERDSQQVALERWLTAFDG-MLAIAPTDTL--TIDAFLNDFNRHL-ANAYDGVRHDSGCPFRWGDKMIAHYQQLGIDPTTKLFIFSDGLDFDQALELCEYFAGRVKISFGIGTFLTNDLANWRNAAGVEYRPLSIVIKLAECQG-----RPVAKISDQPEKAMCEDPIFLANLKR------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4HL7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1817 -17996 -9.90 -51.71 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -9.90 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.382

(partial model without unconserved sides chains): PDB file : Tito_4HL7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HL7-query.scw PDB file : Tito_Scwrl_4HL7.pdb: