Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEK-----STRMYGGTCINIGCIPSKSLIFNGER------------------GIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARFLSNHQIEVTN-NGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPEKLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFHLGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDRGAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVPYSVFITPTLSNVGLTEKQAKAQG--VNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETDLILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK 5U8V Chain:D ((4-463)) MSQKFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDSSYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGV-TSFEGHGKLLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPL-TDDIIVDSTGALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERGFIYVDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHKAQM--NYDLIPSVIYTHPEIAWVGKTEQTLKAEGVEVNVGTFPFAASG--RAMAANDTTGLVKVIADAKTDRVLGVHVIGPSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEALHE---

General information: TITO was launched using: RESULT: Template: 5U8V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 2515 36235 14.41 83.49 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain D : 0.77 3D Compatibility (PKB) : 14.41 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.531

(partial model without unconserved sides chains): PDB file : Tito_5U8V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5U8V-query.scw PDB file : Tito_Scwrl_5U8V.pdb: