Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLPVRKSL-HDAVLQASKADTWEQATKEWNEV-SFI------FNGIGRSNCVCGNAIKYAYELFNGVTGQRL-FPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKAQKKEKIKVNKSNFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEPKKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAKQYADNLVLAMGP------AERAYQDYFGFTET-LTQEERKWE--KILFGKNRAERAIKAKQYQKELEKDQRIASQDTIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYL-----SDHLIDFFYKMKAF-EFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI 5D8M Chain:A ((8-339)) RPVAPLAHAMSPSVLVPAGLAGIQDGRGRFREIMTAIMADHGAFLPGDRSSD--GDGILWRLAGEPGPTGRPVPLGVSTAGIRLVLVPGLLAECVSESSLL----------FDDARPDVERYGYATTLVR-----------------------------TGGRW--GSARNAAIIHEVVAK-------LPENDTIVFVTHSKGAVDVLEALVSYPDLAAR---------TAAVVSVAGAIDGSPLAETFSDGLLRFAESMPLSSCPPGEGTEALDSLKRAYRLRFLAEHR--LPARVRYYSLAAFASREETSAILRPFYDILAKTDALNDGLVI----AADAIIPGGTLLGYPNADHLA-------VAMPFSKKPSLLTSVISKN-----------SYPRPALLEAIARYVEEDL-

General information: TITO was launched using: RESULT: Template: 5D8M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1601 94297 58.90 306.16 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 58.90 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.68 QMean score : ?

(partial model without unconserved sides chains): PDB file : Tito_5D8M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5D8M-query.scw PDB file : Tito_Scwrl_5D8M.pdb: