Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSLNQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG 3VQ6 Chain:A ((4-149)) PGIWQLDCTHL------EGKVILVAVHVASGYIEAEVIPA-ETGQETAYFLLKLAGRW-PV-KTVHTDNGSNFTSTTVKAACDWAGIKQEDGIP-------VIESMNKELKKIIGQV----RDQAEHLKTAVQMAVFIHNH-KRKGGIGGYSAGERIVDI--

General information: TITO was launched using: RESULT: Template: 3VQ6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 632 -60785 -96.18 -437.30 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -96.18 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.254

(partial model without unconserved sides chains): PDB file : Tito_3VQ6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3VQ6-query.scw PDB file : Tito_Scwrl_3VQ6.pdb: