Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIMQIRQFQAQRMQAPRDFTPIENTPICVEIGAGKGKHALLFSGQNPQHTLYAIERTREKFLAMQKQHGLEPRD----NLIPVHADALPWVVHALYPAQVEHFFILYPNPEPHNPAQRWLNMPFFEFLLSRLKTGGTITLAGNIPEYIEEAEQQLLNVWKLPYQKEKIAQTSARTHFEIKYLERGELCQQLIMTKPEGYNTRFDEFAPLQGQIHVE 3P2E Chain:A ((2-216)) LILKGTKTVDLSKDELTEIIG-QFDRVHIDLGTGDGRNIYKLAINDQNTFYIGIDPVKENLFDISKKIIKKPSKGGLSNVVFVIAAAES--LPFELKNIADSISILFPWG-TLLEYVIKPNRDILSNVADLAKKEAHFEFVTTYSDLSKAYFLSEQYKAELSNSGFRIDDVKELDNEYVKQF-NSLWAKRLAFGRKR-------SFFRVSGHV---

General information: TITO was launched using: RESULT: Template: 3P2E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 973 -40309 -41.43 -204.61 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -41.43 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.358

(partial model without unconserved sides chains): PDB file : Tito_3P2E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3P2E-query.scw PDB file : Tito_Scwrl_3P2E.pdb: