Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGLNMPEPTSTTAATTTSLAAVSLLPFINGNALLGAVLGA--AFVAYLEKDLSAKQRIVFMLLCVGFGYLLGPEITSRTQYISSDATASMVAAIFAIYILIKLLDWVKNSTLAQLWKTFRGGGNS 2YQR Chain:A ((1-119)) -GSSGSSGGMHYVQDKLFVGLEHAVPTFN---VKEKVEGPGCSYLQHIQIETGAKVFLRGKGSGCIEPASGREAFEPMYIYISHPKPEGLAAAKKLCENLLQTVHAEYSRFVNQINTAVPLPG--

General information: TITO was launched using: RESULT: Template: 2YQR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 414 -27419 -66.23 -234.35 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -66.23 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.327

(partial model without unconserved sides chains): PDB file : Tito_2YQR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YQR-query.scw PDB file : Tito_Scwrl_2YQR.pdb: