Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)


Input alignment information:
Query sequenceMATPVTDPPKIIGRELHLDRLIGSGGFGEVYLAVRTKLATNPKHNFTFPAECVVKVMRRGLCTEEDVAAMNREVATLSSMDHPYIVAYIGAWVEAARGKFFGCYCLAMKYCEGGDLHGFIAQCIKAHRLPPVDVAVRIMAQVFSALNYSHSRRLIHRDIKPGNVFLTLQKSGVPDKAMVGDYGLVRSLEATRQLVKTRVGTPTYISPEIAAGEAYSTKTDIFSAGTMFYELLSLHRPFWKRMMTDQQLFREVLHRDPMPQFRAYTSSVYGTALADVIEACLTKHEANRATAYDALVRLTSPITAYVLKYAIPVYPEKDALTTSPPRPPAASSAPDGHASAADADGDAATARQRLERLFLVRKGTAVGARLTRLLSHNAELLFQVRVLVACRSDNTDHLENGLAELLWAFPDAEVPFQEVIDLVMSDYRQLAE
1TKI Chain:A ((20-275))-----------LYEKYMIAEDLGRGEFGIVHRCVETSSK----------KTYMAKFVKVKG---TDQVLVKKEISILNIARHRNILHLHESFESM------EELVMIFEFISGLDIFERINTS---AFELNEREIVSYVHQVCEALQFLHSHNIGHFDIRPENIIYQTRR---SSTIKIIEFGQARQLKPG-DNFRLLFTAPEYYAPEVHQHDVVSTATDMWSLGTLVYVLLSGINPFLAET--NQQIIENIMNAEYT--FDEEAFKEISIEAMDFVDRLLVKERKSRMTASEALQH---------------------------------------------------------------------------------------------------------------------------------------


General information:
TITO was launched using:
RESULT:

Template: 1TKI.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output 		Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1185 -150433 -126.95 -587.63
target 2D structure prediction score : 0.53
Monomeric hydrophicity matching model chain A : 0.64

3D Compatibility (PKB) : -126.95
2D Compatibility (Sec. Struct. Predict.) : 0.53
1D Compatibility (Hydrophobicity) : 0.64
QMean score : 0.302

(partial model without unconserved sides chains):
PDB file : Tito_1TKI.pdb:





(Unconserved sides chains are recalculated) :
Sequence: align-1TKI-query.scw
PDB file : Tito_Scwrl_1TKI.pdb: