Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----------WTGKS---EASNRPPPGRRPEETTWFTS-DPSYACGVKIFRPGS----EGSSGLAEITHLNFHEKI--KVLK---GQYECEVGPSCSTLRCTMPRGWRLDIFGKSFPTRRTTYFAENGNPEYNTLASEANIPLYDCRVVIRFPPTGGRDTGPLAEATHFNLGEVVGVLG------GRHTCQAQGQCANVNCNVPKGYTYYSLTGGPFQTKEKSHTFQSDA- 1L6Z Chain:A ((1-203)) EVTIEAVPPQVAEDNNVLLLVHNLPLA---LGAFAWYKGNTTAIDKEIARFVPNSNMNFTGQAYSGREIIYSNGSLLFQMITMKDMGVYTLDMTDENYRRTQATVRFHVHQPVTQPFLQVTNTTVKELDSVTLTCLSNDIGA-----NIQWLFNSQSLQLTE---RMTLSQNNSILRIDPIKREDAGEYQCEIS--------N----------PVSVRRSNSIKLDIIFDPS

General information: TITO was launched using: RESULT: Template: 1L6Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 720 6919 9.61 40.22 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : 9.61 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.136

(partial model without unconserved sides chains): PDB file : Tito_1L6Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L6Z-query.scw PDB file : Tito_Scwrl_1L6Z.pdb: