Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAACTARRALAVGSRWWSRSLTGARWPRPLCAAAGAGAFSPASTTTTRRHLSSRNRPEGKVLETVGVFEVPKQNGKYETGQLFLHSIFGYRGVVLFPWQARLYDRDVASAAPEKAENPAGHGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHEDILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYCIRLENL----DSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFER--PDGSHFDVRIPPFSLESNKDEKTPPSGLHW 5HDW Chain:A ((2-131)) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EFVATTGDITVSVSTSFLPELSSVHPPHYFFTYRIRIEMSKDALPEKACQLDSRYWRITNAKGDVEEVQGPGVVGEFPIISPGR-VYEYTSCTTFSTTSGYMEGYYTFHFLYFKDKIFNVAIPRFHMACPT-----------

General information: TITO was launched using: RESULT: Template: 5HDW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 565 -13533 -23.95 -109.13 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -23.95 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.413

(partial model without unconserved sides chains): PDB file : Tito_5HDW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5HDW-query.scw PDB file : Tito_Scwrl_5HDW.pdb: