Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WYHGLLSRQKAEALL--QQNGDFLVRASGSRGGNPVISCRWRGSALHFEVFRVALRPRPGRPTALFQLEDEQFPSIPALVHSY 1R1S Chain:C ((11-85)) WFHEGLSRHQAENLLMGKDIGFFIIRASQSSPGDFSISVRHEDDVQHFKV----MRDTKGN----YFLWTEKFPSLNKLVDYY

General information: TITO was launched using: RESULT: Template: 1R1S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 257 -738 -2.87 -10.10 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain C : 0.74 3D Compatibility (PKB) : -2.87 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.612

(partial model without unconserved sides chains): PDB file : Tito_1R1S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1R1S-query.scw PDB file : Tito_Scwrl_1R1S.pdb: