Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRFELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNN-VSVD---GYTIEAEAGANLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTK-DGEIETLSAKDLAFGYRHSAIQE-S-GAVVLSVKFALAPGTH-------------QV-I-----KQEMDRLTHLRELKQP--LEYPSCGSVFKRPVG--------------------------HFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQSVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR 4JAY Chain:C ((4-340)) -------------LELQEHCSLKPYNTFGIDVRARLLAHARDEADVREALALARERGLPLLVIGGGSNLLLTR-DVEALVLRMASQGRRIVSDAADSVLVEAEAGEAWDPFVQWSLERGLAGLENLSLIPGTVGAAPMQNIGAYGVELKDVFDSLTALDRQDGTLREFDRQACRFGYRDSLFKQEPDRWLILRVRLRLTRRERLHLDYGPVRQRLEEEGIASPTARDVSRVICAIRREKLPDPAVLGNAGSFFKNPLVDATQAERLRQAFPDLVGYPQADGRLKLAAGWLIDKGGWKGFRDGPVGVHAQQALVLVNHGGATGAQVRALAERIQEDVRRRFGVELEPEPNLY-------------------

General information: TITO was launched using: RESULT: Template: 4JAY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1384 -54089 -39.08 -191.13 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain C : 0.75 3D Compatibility (PKB) : -39.08 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.543

(partial model without unconserved sides chains): PDB file : Tito_4JAY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JAY-query.scw PDB file : Tito_Scwrl_4JAY.pdb: