Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQIYLNGELTDTPSQNLLQLIQELALE--------------GKRFAVEHNQQIVPKSKLEQISIAQHDRIEIIHAVGGG 4N6E Chain:B ((22-90)) ----------EAKGATVLEIIDDVESRHAGIKARLVKEEKLHRFINVYVNDEDVRFSGGLEAEVKDGDTLTILPAVAGG

General information: TITO was launched using: RESULT: Template: 4N6E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 166 5153 31.04 93.68 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : 31.04 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.355

(partial model without unconserved sides chains): PDB file : Tito_4N6E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4N6E-query.scw PDB file : Tito_Scwrl_4N6E.pdb: