Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDSNMEVLIKTEDAIDAYNGAANLARSLGVSRAAISQWGEYVPEVSARGLVIL---QPSIPHIIKKPSAT 1RZS Chain:A ((1-61)) --------MYKKDVIDHFGTQRAVAKALGISDAAVSQWKEVIPEKDAYRLEIVTAGALKYQENAYRQAA-

General information: TITO was launched using: RESULT: Template: 1RZS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 213 -27796 -130.50 -479.24 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -130.50 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.475

(partial model without unconserved sides chains): PDB file : Tito_1RZS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1RZS-query.scw PDB file : Tito_Scwrl_1RZS.pdb: