Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNHMVTTKKAKVQFNWQDPFLIEQQLSPDERMIHDAAHAYCQERLQPRVLEQFRHETTDPSIFREMGELGLLGPTIPEQYGGAGLNYVSYGLVAREIEYVDSGYRSMASVQSSLVMVPIHEFGTEEQKQKYLPKLATGEYIGCFGLTEPDHGSDPGSMITRAKKVEGGYRLTGAKMWITNSPIADVFVVWAKEVSAEGNVGDICGFILEKGWEGLSAPAIHGKVGLRASITGEIVMDNVFVPEENAFPEIRGLKGPFTCLNSARYGIAWGAMGAAEFCWHTAHQYTMDRKQFGRPLAANQLIQKKLADMQTEIALGLQAALRFGRMKDEGIASVEGTSLIKRNNCGKALDIARMARDMMGGNGISDEFGVARHLVNLEVVNTYEGTHDVHALILGRAQTGIAAFSN 3EON Chain:C ((5-394)) -----------ATFHWDDPLLLDQQLADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAIFREMGEIGLLGPTIPEQYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFGLTEP------GSMVTRARKVPGGYSLSGSKMWITNSPIADVFVVWAK--LDEDGRDEIRGFILEKGCKGLSAPAIHGKVGLRASITGEIVLDEAFVPEENILPHVKGLRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNG--DEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQA---

General information: TITO was launched using: RESULT: Template: 3EON.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 2092 -169466 -81.01 -443.63 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain C : 0.93 3D Compatibility (PKB) : -81.01 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.93 QMean score : 0.494

(partial model without unconserved sides chains): PDB file : Tito_3EON.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EON-query.scw PDB file : Tito_Scwrl_3EON.pdb: