Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNGHVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEGSGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKSVEELIG 4B3M Chain:E ((4-151)) ---------DFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLR---------

General information: TITO was launched using: RESULT: Template: 4B3M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain E - contact count / total energy / energy per contact / energy per residue : 766 -75392 -98.42 -509.40 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain E : 0.83 3D Compatibility (PKB) : -98.42 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.525

(partial model without unconserved sides chains): PDB file : Tito_4B3M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4B3M-query.scw PDB file : Tito_Scwrl_4B3M.pdb: