Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLPPETLEEELDYIYESNNN---LLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWGMGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDLGEFLDVYKMSYLIE 2VI7 Chain:C ((35-168)) ----------------------------------------LQMPYQSVEQRRKRLHDS-DDDRLLILVALHQGDVIGSASLEQHPRIRRSHSGSIGMGVAVAWQGKGVGSRLLGELLDIADNWMNLRRVELTVYTDNAPALALYRKFGFETEGEMRDYAVRD-GRFVDVYSMARL--

General information: TITO was launched using: RESULT: Template: 2VI7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 486 1104 2.27 8.49 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain C : 0.72 3D Compatibility (PKB) : 2.27 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.387

(partial model without unconserved sides chains): PDB file : Tito_2VI7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VI7-query.scw PDB file : Tito_Scwrl_2VI7.pdb: