Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSRPCLLLLGIDVVFAHISGSCINHVGRADLVMLRRGFCRSIPLLGPTFTELVERLDSFEKEFIEWKAFRKAVESTSPKVTEAAKEIIAESMKEVKTSKVNLENPLTPEEFTELNQFYAKQKVKDIFFENLLYINTP-NDLMQHSETVFRQYLVRIARRVRHLNHAPYGLSQMPGIQMLKKWYQWSFHDVRSTPVP--TTRDECYRCDRMVRRVFLRHYNVSSLITDGMVEFASREGWTHVDEEVMRTYDELQNFFEAFCLGRVRLRFL-VGNYMYLSTKILGVSKEEYAVNDPDGLTVPIFFDHNAEDFVGQICKKCSLLVLTKCAIKEAQASYD------AEIELK---LAG-DPNLVFVGIPYITYDIICAMLEDAVSANVDRQERTGKACTKIEVTLAQWPTNKRFVLRISDTAGGMTLRQASKQLSCWSLYRNIQGHNQDTISTWTSSPIRLPYAYNAARVIGGNITLASIEGYGTDRQLYLPSTGLAGVSL 3D2R Chain:B ((4-360)) ---------------------------------------------------------------------------------------------------------------PREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQGIIEYK-ACTV---D---PVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTG-----------------------NPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQEN-QPSLTPIEVIVV--LGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTP--------PLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSE----

General information: TITO was launched using: RESULT: Template: 3D2R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1487 -45675 -30.72 -139.68 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.65 3D Compatibility (PKB) : -30.72 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.446

(partial model without unconserved sides chains): PDB file : Tito_3D2R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3D2R-query.scw PDB file : Tito_Scwrl_3D2R.pdb: