Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence PSEMRFANAWLAFVPVATQALGVAAELCTI----DILFRGRRVTFRNIPSGSFQQTEVQGKRCIISVDDSCQPTQVGLD-QNYWSVKLREEALGL 4TZC Chain:A ((2-107)) -TSLCCKQCQETEITTKNEIFSLSLETLTVYKASNLNLIGRPSTVHSWFPG-YAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLT--RSALLP

General information: TITO was launched using: RESULT: Template: 4TZC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 381 -16954 -44.50 -197.14 target 2D structure prediction score : 0.36 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -44.50 2D Compatibility (Sec. Struct. Predict.) : 0.36 1D Compatibility (Hydrophobicity) : 0.69 QMean score : -0.095

(partial model without unconserved sides chains): PDB file : Tito_4TZC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4TZC-query.scw PDB file : Tito_Scwrl_4TZC.pdb: