Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQEVYCVMIEKSINPHDYQHIHSPASVMPKNYHAKHRIDLHQHERGQLIYATSGIMELSTEEELWLIPPRFGVWIPAYTPHQMTTKTDVHLNTLYIDTYRWSKPFPDKPCGVTVSGLLHELLIRAASFPIEYPLHSVEWKTMDLLVEELKWTKGISLMTPEPYMDKRLQDLCNILIINPAD-NHSLEEWSSQVGATTRTLSRLFKQEMNTTFTLWRQQLRIVHAIPSLMAG-KPISDISQELGYSSQSTFTVMFKKIMGKTPTEYIAWANGNPTTFD 2K9S Chain:A ((2-106)) --------------------------------------------------------------------------------------------------------------------------------------------------------------------DNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQLGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEFRAGC--------

General information: TITO was launched using: RESULT: Template: 2K9S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 336 15869 47.23 154.06 target 2D structure prediction score : 0.79 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : 47.23 2D Compatibility (Sec. Struct. Predict.) : 0.79 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.641

(partial model without unconserved sides chains): PDB file : Tito_2K9S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2K9S-query.scw PDB file : Tito_Scwrl_2K9S.pdb: