Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPTEVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKDSNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLN--MNTPTIIIVHQDIPGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSR--NCDEAIEEIRKIPHLHNVNFFK 3K5P Chain:A ((328-416)) ----------------------------------------------------------------------------------------------------------------------------------------GAVNFPQVQLPPRPTGTRFMHVHENRPGILNSLMNVFSHHHINIASQFLQ--TDGEVGYLVMEADGVGEASDAVLQEIREIPGTIRARLLY

General information: TITO was launched using: RESULT: Template: 3K5P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 359 -11758 -32.75 -138.33 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -32.75 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.726

(partial model without unconserved sides chains): PDB file : Tito_3K5P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3K5P-query.scw PDB file : Tito_Scwrl_3K5P.pdb: