Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHCLMLSQNHLVPL-ENFQSGIIIHIEVE--DVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQGPAGLVLDFYRMK 4JH6 Chain:A ((3-119)) NGINHLCFSVSNLEDSIEFYEKVLEGELLVRGRKLAYFNICGVWVALNEEIHIPRNEIYQSYTHIAFSVEQKDFESLLQRLEENDVHILKGRERDVRDCESIYFVDPDGHKFEFHSG-

General information: TITO was launched using: RESULT: Template: 4JH6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 414 -39664 -95.81 -347.93 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -95.81 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.507

(partial model without unconserved sides chains): PDB file : Tito_4JH6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JH6-query.scw PDB file : Tito_Scwrl_4JH6.pdb: