Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----------------------------------MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH--FAHKSLKDCDF--FFENESPEHL---------ANKESLYHWLKKETKVQLEYPLSELK--QIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGFYVWELDKGKQVLRLKYLIYQDLRGK-LHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV-----SEDKDICRYIRQQLYY------QNLFWMKEQAEAYQKGENILTYGL----KEWYPQIRPIVGKFFQIEQDLTSYYQ---HFYTYYQKN--PQNDWQKLYPPAFYQQYFLKNMVE-- 5MPT Chain:A ((7-385)) LGGSILPKSAILDAFRIAKEATDDFILNGQLGTYYNEVMPRSTELCVAHIVNAFEQLGCPIRSAAAYQRLERVPYLPKHERFMNLIYGLLEEARLIDINGSEITRTSVPVSTKSVETMLEELLHDEPLHAAEHKLTSLTGSKFADCITGKEDGLQLIFGS--PEGREIVTDVYAKSPINAVWIQQAEFFLEQLVKRLP------NTGEPLRILEMGAGTGGTTVKMLPLLERLGVPVEYTMTDLS---SSLIAAARKRFKKYPFMKFKVVNIESPPDPQLVHSQHIILATNCVHATRNLEISTRNIHRILRPDGFLLLLEMTEQVPWVDFIFGLLEGWWLFEDGRRHALQPATHWKKILTSVGYGHVDWTEGTRPEANIQRLIIALASEP

General information: TITO was launched using: RESULT: Template: 5MPT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1352 -5852 -4.33 -19.12 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -4.33 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.283

(partial model without unconserved sides chains): PDB file : Tito_5MPT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5MPT-query.scw PDB file : Tito_Scwrl_5MPT.pdb: