Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEYYPLQELFG---TSKTIVNRGIRGYQTGLLLENLDAH-LYGGAVDKIFLLIGTNDIGKDVPVNEALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQELASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY 1VYH Chain:N ((37-213)) ----------------------------DKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHEN--TAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPN-------PLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELI-

General information: TITO was launched using: RESULT: Template: 1VYH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain N - contact count / total energy / energy per contact / energy per residue : 842 -16035 -19.04 -92.68 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain N : 0.70 3D Compatibility (PKB) : -19.04 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.534

(partial model without unconserved sides chains): PDB file : Tito_1VYH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VYH-query.scw PDB file : Tito_Scwrl_1VYH.pdb: