Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNRQQIDVLVKQMNIDTAKGEVDARVQQIVVRLLGDLFQAIEDLDIQPSEVWKGLEYFTDAGQANELGLLAAGLGLEHYLDLRADEADAKAGMTGGTPRTIEGPLYVAGAPESVGFAHMDDGTETGKIDTLIIEGTVTDTDGNIIENAKVEVWHANSLGNYSFFDKS--QSDFNLRRTIFTDADGKYVALTTMPVGYGCPPEGTTQALLNKLGRHGNRPSHVHYFVSAPGYRKLTTQFNIEGDEYLWDDFAFATRDGLVATAVDVTDPAEIQRRGLDHAFKHITFNIELVKEATAAPSTEVERRRASA 5TD3 Chain:B ((38-319)) ----------------------DARTQQIVLRLLGDLFKAIDDLDITPDEVWAGVNYLNKLGQDGEAALLAAGLGLEKYLDIRMDAADAALGLDGGTPRTIEGPLYVAGAPVRDGVAKIDLDADAGA-GPLVIHGTVKDLDGKPVAGALVECWHANSHGFYSHFDPTGAQRDFNLRGAVRTGADGTYAFRTLMPVGYGCPPQGATQQLLDRLGRHGNRPAHVHFFVTSDGHRKLTTQFNIEGDPLIWDDFAYATREELIPPVTTKTGGAALGLKA--DAYQDITFDFVLTPRV--ADNQIVERPRAS-

General information: TITO was launched using: RESULT: Template: 5TD3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1338 -35296 -26.38 -126.96 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : -26.38 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.558

(partial model without unconserved sides chains): PDB file : Tito_5TD3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5TD3-query.scw PDB file : Tito_Scwrl_5TD3.pdb: