Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFE---NSFSRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD 3TDS Chain:C ((3-259)) ----------------------RAHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILLIFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIKDTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRGILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAIITSGFEHSVANMTIYSVSLFSPTI--STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEK-----

General information: TITO was launched using: RESULT: Template: 3TDS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1386 -169068 -121.98 -665.62 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain C : 0.79 3D Compatibility (PKB) : -121.98 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.303

(partial model without unconserved sides chains): PDB file : Tito_3TDS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TDS-query.scw PDB file : Tito_Scwrl_3TDS.pdb: