Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISMKVVFHIDELE--KWSETGKNVKNLIKASPETTIVVSVNGIAITGYLDSAN-------------------------------AEFL---DLQG-VVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYIKP 2QS7 Chain:D ((7-142)) --KKKLSIIVFSGTIDKLMPVGILTSGAAAS--GYEVNLFFTFWGLQAITKRSLNSQQPPQIDKNYEQMGPIMMQKMQEMKYPMWHQLVQQAKEIGEVKVFACSTTMEFFGIKREDLAEFVD-DVVGVATFLDRAEGGTTL---

General information: TITO was launched using: RESULT: Template: 2QS7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 379 -10572 -27.89 -106.79 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain D : 0.61 3D Compatibility (PKB) : -27.89 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.472

(partial model without unconserved sides chains): PDB file : Tito_2QS7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QS7-query.scw PDB file : Tito_Scwrl_2QS7.pdb: