Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDVRKSLQTILLKEAISMKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKVTASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSARLDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDTLLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQLGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANGNVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNK--------RVRADLVFYLPKRVYDHAAIKLLNGNIMI--ETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGNIDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKED--NLKKVEASSVNGNVKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQV--QLSTTTGSIYLKDTDK 4QRK Chain:A ((12-219)) ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEIKIVEPNGAEKTKLNLNFGVGKLNISGNEEKLMKGKFIYSEN---EWKP--EI--KYEVKDKDGELEISQPGLKSGNVSLNNKRNEWNINLNEKIPTEIKLSLGTGEFKADLSKINLKELNVGM-------------------GVGKVD-------------------------------------LDISGNYKNNVKVNIEGGVGEATVYLPKSIGVKIKAEKGVGAVNANGFI--VE-G----ENIYKNSQY--GKSKNSIEVNIEAGVGAINIKQ---

General information: TITO was launched using: RESULT: Template: 4QRK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1052 65072 61.86 335.42 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 61.86 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.247

(partial model without unconserved sides chains): PDB file : Tito_4QRK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4QRK-query.scw PDB file : Tito_Scwrl_4QRK.pdb: