Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNQLDQRPIIALDFSTRQEVEDFL-RFFPKEEKLFVKIGMELFYQEGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAAMRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYA----SCAKKAGLDGVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGRPITQSTNPYKAYQTIQTEWS 1EIX Chain:D ((18-238)) --------VVALDYHNRDDALAFVDKIDPRDCRL--KVGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASGGARMMTAAREAL---VPFGKDAPLLIAVTVLTS-----MEASDLVDLGMTLSPADYAERLAALTQKCGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSEAGDQRRIMTPEQALSAGVDYMVIGRPVTQSVDPAQTLKAIN----

General information: TITO was launched using: RESULT: Template: 1EIX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1184 -11036 -9.32 -51.09 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain D : 0.82 3D Compatibility (PKB) : -9.32 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.569

(partial model without unconserved sides chains): PDB file : Tito_1EIX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1EIX-query.scw PDB file : Tito_Scwrl_1EIX.pdb: