Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEEVKQIIDYCR----IHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGASLIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLE-DGTLKTLTKDEMVFSYRHSKVQE------LRAIVLEARFSLQTG-D--Y---EA-I------------KARMDE-LTELRQSK----QP--LEYPSCGSVFKRPVG---------------------------HYTGQLIQQAGL-QGLKWGG---AQVSEKHAGFIVNIDHATATDYIELIAHIQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN 5JZX Chain:A ((39-404)) --RSGVGSLFAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAENLTDLTVVRLA-NSGITIDGNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLKHADGLAVP-TVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRPVPHYPAPDGVKLAAGWLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGCM------------

General information: TITO was launched using: RESULT: Template: 5JZX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1564 -24566 -15.71 -83.27 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -15.71 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.457

(partial model without unconserved sides chains): PDB file : Tito_5JZX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5JZX-query.scw PDB file : Tito_Scwrl_5JZX.pdb: