Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKFTTYTTFPEQTSNESLWILVDSEQLQSNLNTYQINNLESILTATQFKANFNETLPLFGQLSTQPHSQLLGLGKAAELQAAKLAKLAQTIIKSAQN-KFKHIAIDIAAL---PVEYHYLFALSLTQAAYGYDEFKSTKNEFVLQ----QVDLI-SSQ-TSLDENQLALVHAVQSGQSYARDLGNRPGNICFPEYLAEQALALAAEFPDLLKVTVLNEQQMADLGMYAFLAVSKGS--ERPGRIVTLEYQAQLEQAPVVLVGKGVTFDTGGISLKPGLGMDEMKFDMCGAASVLGTIRALCEARLPIHVVGAIAAAENMPSGKATRPGDIVTTMSGQTVEILNTDAEGRLVLCDTLTYIKRFNPAVVIDIATLTGACVVALGKVLSGLFSPDDTLAAELQQAGEQSFDRVWRMPVIDDYQELLDSPFADIANIG-GPHGGAITAACFLERFTR---DYRWAHLDVAGTAWLSG----SAKGATGRPVPLLMQFLANRVSTNG 4ZLA Chain:B ((8-501)) LKIKLEKTTFENAKAECSLVFIINKDFS-----HAWVKNKELLE--TFKYEGEGVF---LD--QENKILYAGVKEDD---VHLLRESACLAVRTLKKLAFKSVKVGVYTCGAALLENLKALFLGLKLGLYEYDTFKSNKKESVLKEAIVALELHK---LEKSAKEALKYAEIMTESLNIVKDLVNTPPMIGTPVYMAEVAQKVAKE-N-HLEIHVHDEKFLEEKKMNAFLAVNKASLSVNPPRLIHLVYKPKKAKKKIALVGKGLTYDCGGLSLKPADYMVTMKADKGGGSAVIGLLNALAKLGVEAEVHGIIGATENMIGPAAYKPDDILISKEGKSIEVRNTDAEGRLVLADCLSYAQDLNPDVIVDFATLTGACVVGLGEFTSAIMGHNEELKNLFETSGLESGELLAKLPFNRHLKKLIESKIADVCNISSSRYGGAITAGLFLNEFIRDEFKDKWLHIDIAGPAYVEKEWDVNSFGASGAGVRACTAFVEELLKK--

General information: TITO was launched using: RESULT: Template: 4ZLA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2777 -64433 -23.20 -140.07 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain B : 0.76 3D Compatibility (PKB) : -23.20 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.492

(partial model without unconserved sides chains): PDB file : Tito_4ZLA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ZLA-query.scw PDB file : Tito_Scwrl_4ZLA.pdb: