Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence NCEITILQGESRIGFVNVPSSGKVRENIRNWWYTISCDEDCNPKISGFTYTVEKA-----------C 1HX2 Chain:A ((1-60)) ----NFVCPPGQTFQTCASSCPKTCETRNK---LVLCDKKCNQRCGCISGTVLKSKDSSECVHPSKC

General information: TITO was launched using: RESULT: Template: 1HX2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 180 1042 5.79 21.27 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 5.79 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.227

(partial model without unconserved sides chains): PDB file : Tito_1HX2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1HX2-query.scw PDB file : Tito_Scwrl_1HX2.pdb: