Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence VRICSLALGKIINGEVTEYLED---TLQQLPGPAGNVVLEYEDFSIQ--------LSLTKNCWPKLKRGS----VVPKGYSLHVYSPTIEGHAATSAVLEGDDRLMLPGFDPLKMRVQFYEWLVGLSWKPLKKGP---- 4FPR Chain:A ((19-148)) AYVCREAS---ISGEIR-YPQGTCPTKTEALNDCNKVTKGLIDFSQSHQRAWGIDMTAKVQCAPCKTTDPWDVVLCTCKITAHRYREFVPKIPYSS--FSSAPGVIFRQETGLD---HDPEWVVNMKARTRGCDHHHHH

General information: TITO was launched using: RESULT: Template: 4FPR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 456 3342 7.33 30.10 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 7.33 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.185

(partial model without unconserved sides chains): PDB file : Tito_4FPR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4FPR-query.scw PDB file : Tito_Scwrl_4FPR.pdb: