Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSISMLKKYPC-TMQHDQSDCAAAVVSTVLLSYKKE--LSIMKIREIIGTD-------MYGTTVSGIVSGLNKLNFTVKAVRVALED 1X9Y Chain:B ((227-302)) ----TLKNFKIREQQFDNSWCAGFSMAALLNATKNTDTYNAHDIMRTLYPEVSEQDLPNCATFPNQMIEYGKSQGRDIHY-------

General information: TITO was launched using: RESULT: Template: 1X9Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 205 -14876 -72.57 -225.39 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain B : 0.64 3D Compatibility (PKB) : -72.57 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.580

(partial model without unconserved sides chains): PDB file : Tito_1X9Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1X9Y-query.scw PDB file : Tito_Scwrl_1X9Y.pdb: