Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MELVLPNNYVVI-DEEEMMYL-DGGAIYIPRWAITGAI--------TGAAYAALAAAGGGGLQLVLASYGLRSALVAG-IVK--GLGVLGIHI------GNAFANTVIR-S----IASAGIGAGADWIFTNIIDGWDGRRDNQLRIG--------------------- 1QCZ Chain:A ((7-168)) -----PARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAESAEENGYQVIIAGAG-GAAHLPGMIAAKTLVPVLGVPVQSAALSGVDSLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVLENPDPRGA

General information: TITO was launched using: RESULT: Template: 1QCZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 585 -35550 -60.77 -303.84 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -60.77 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.163

(partial model without unconserved sides chains): PDB file : Tito_1QCZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QCZ-query.scw PDB file : Tito_Scwrl_1QCZ.pdb: