Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTVLEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQALRNRT-PIETDPKLDTLAKFTLAVINTK-GRVGDEALSEFLEAGYTQQNALDVVFGVSLAILCNYANNLANTPINPELQPYA 2GMY Chain:A ((3-148)) --------------------------------TRINYAKASPEAFKAVMALENYVQSSGLEHRFIHLIKLRASIINGCAFCVDMHVKESR-HDGLSEQWINLMSVWRESPVYTEQERALLGWVDAVTKIAETGAPDDAFETLR-AHFSDEEIVKITVAIGAINTWNRIAVGFRSQHPVEA----

General information: TITO was launched using: RESULT: Template: 2GMY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 550 -49898 -90.72 -346.51 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -90.72 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.448

(partial model without unconserved sides chains): PDB file : Tito_2GMY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2GMY-query.scw PDB file : Tito_Scwrl_2GMY.pdb: